The planet is being invaded by parasitic shape-changing aliens who have a taste for spinal fluid. While many of their victims die, the survivors find themselves with superpowers. These new heroes (among them Tommy Monaghan) must band together with the old to repel the alien invasion.
This is the 1st Chapter of the Bloodlines cross over. It continues in EarthPlague.
The reading order for this arc is as follows:
Part 1) Lobo Annual #1
Part 2) Superman: The Man of Steel Annual #2
Part 3) Batman: Shadow of the Bat Annual #1
Part 4) Flash Annual #6
Part 5) New Titans Annual #9
Part 6) Superman Annual #5
Part 7) Green Lantern Annual #2
Part 8) Batman Annual #17
Part 9) Justice League International Annual #4