Due to illegal chemical dumping, three new mutants are created, with a mean-on for mankind.
A year later, April winds up stuck in a creepy little town in the middle of nowhere (due to a flat tire). The townspeople poison April. April gives them the slip momentarily and calls for help from the Turtles. Turtles show up just in time to stop the mutant creatures from making April drink toxic waste. Battle ensues. Bad guys take off. Good prevails.