Iron Man is contacted telepathically by Drax the Destroyer, warning him of the Blood Brothers coming to Earth! Unfortunately, the warning comes too late and Iron Man is captured. Returning him to Titan, Iron Man's armor allows for Drax to be freed from his prison cell. Learning about the history of Titan and Thanos, Iron Man and Drax are confronted by a robotic duplicate of Thanos who activates a self-destruct mechanism on Thanos' fortress! Can Drax and Iron Man escape in time?
Although this issue reprints what is traditionally considered to be the first appearance of Thanos, he does not appear in this issue other than in flashbacks; a robot duplicate of Thanos appears. The first full appearance of Thanos is Captain Marvel (1968) #27.
Chronos & Starfox (as Eros) appear only in flashback.