Mysterious shrines are appearing across the Midwest-shrines to frog-like gods that mean gruesome death for anyone who encounters them. But before the Bureau for Paranormal Research and Defense can pursue this threat, Johann is overcome by a mysterious presence lurking deep beneath the new B.P.R.D. headquarters. Meanwhile, Abe Sapien wrestles with demons of his own in an old house on the coast of Rhode Island. The secrets of his past are not only revealed to him, but take terrible form before his very eyes.